I am convinced that simplicity is the key to usability, accessibility and a great user experience. But to create the perfect minimalism can easily become the most difficult task.
A good start could be to follow Krug's third law of usability:
"Get rid of half the words on each page, then get rid of half of what's left"
This does not only apply to bodycopy though. It might be a good idea to check if all design elements on a page serve a purpose as well; a purpose for the user that is, not for the business.
To put the focus on the users needs will ultimately serve the business much better, since a happy customer, who found all desired information in an easy and pleasant way, is the most valuable asset any business can have.